tailieunhanh - Báo cáo y học: " The mode of lymphoblastoid cell death in response to gas phase cigarette smoke is dose-dependent"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:"The mode of lymphoblastoid cell death in response to gas phase cigarette smoke is dose-dependent. | Respiratory Research BioMed Central Research The mode of lymphoblastoid cell death in response to gas phase cigarette smoke is dose-dependent Nadia D Sdraliaf1 Alexandra L Patmanidif1 Athanassios D Velentzas2 Loukas H Margaritis2 George E Baltatzis1 Dimitris G Hatzinikolaou3 and Anastasia Stavridou 1 Address institute of Biomedical Research and Biotechnology 55 Solomou Str Athens 10432 Greece 2Faculty of Biology Department of Cell Biology and Biophysics University of Athens Athens 15781 Greece and 3Faculty of Biology Department of Botany University of Athens Athens 15781 Greece Email Nadia D Sdralia - sdralia@ Alexandra L Patmanidi - alexpatmanidi@ Athanassios D Velentzas - tveletz@ Loukas H Margaritis - lmargar@ George E Baltatzis - gbaltatzis@ Dimitris G Hatzinikolaou - xatzdim@ Anastasia Stavridou - nstavr@ Corresponding author tEqual contributors Open Access Published 10 September 2009 Received 4 December 2008 Respiratory Research 2009 10 82 doi l465-992l-l0-82 Accepted I0 September 2009 This article is available from http content l0 l 82 2009 Sdralia et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Background Cigarette smoke CS is the main cause in the development of chronic obstructive pulmonary disease COPD the pathogenesis of which is related to an extended inflammatory response. In this study we investigated the effect of low and high doses of gas phase cigarette smoke GPS on cultured lymphocyte progenitor cells using techniques to assess cell viability and to elucidate whether cells die of apoptosis or necrosis upon exposure to .