tailieunhanh - Báo cáo y học: " Corticomotor control of the genioglossus in awake OSAS patients: a transcranial magnetic stimulation study"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:" Corticomotor control of the genioglossus in awake OSAS patients: a transcranial magnetic stimulation study. | Respiratory Research BioMed Central Open Access Corticomotor control of the genioglossus in awake OSAS patients a transcranial magnetic stimulation study Frédéric Series 2 Wei Wang41 3 and Thomas Similowskh2 4 Address 1Centre de recherche Hôpital Laval Institut universitaire de cardiologie et de pneumologie de 1 Université Laval Quebec City Quebec Canada 2UPMC Université Paris 6 Pierre et Marie Curie EA 2397 Paris France 3The 1st Affiliated Hospital of China Medical University Shen Yang City Liao Ning Province PR China and 4Assistance Publique - Hôpitaux de Paris Groupe Hospitalier Pitié-Salpêtrière Service de Pneumologie et Réanimation Paris France Email Frédéric Series - Wei Wang - wwbycmu@ Thomas Similowski - Corresponding author fEqual contributors Published 13 August 2009 Received 16 March 2009 Respiratory Research 2009 10 74 doi l465-992l-l0-74 Accepted I3 August 2009 This article is available from http content l0 l 74 2009 Sériès et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Upper airway collapse does not occur during wake in obstructive sleep apnea patients. This points to wake-related compensatory mechanisms and possibly to a modified corticomotor control of upper airway dilator muscles. The objectives of the study were to characterize the responsiveness of the genioglossus to transcranial magnetic stimulation during respiratory and non-respiratory facilitatory maneuvers in obstructive sleep apnea patients and to compare it to the responsiveness of the diaphragm with reference to normal controls. Methods Motor evoked potentials of the genioglossus and of the diaphragm with the .