tailieunhanh - Báo cáo y học: " Candida soluble cell wall β-glucan facilitates ovalbumin-induced allergic airway inflammation in mice: Possible role of antigen-presenting cells"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:"Candida soluble cell wall β-glucan facilitates ovalbumin-induced allergic airway inflammation in mice: Possible role of antigen-presenting cells. | Respiratory Research BioMed Central Open Access Candida soluble cell wall p-glucan facilitates ovalbumin-induced allergic airway inflammation in mice Possible role of antigen-presenting cells Ken-ichiro Inoue 1 Hirohisa Takano1 Eiko Koike1 Rie Yanagisawa1 Toshio Oda2 Hiroshi Tamura2 Yoshiyuki Adachi3 Ken-ichi Ishibashi3 and Naohito Ohno3 Address Environmental Health Sciences Division National Institute for Environmental Studies Tsukuba Ibaraki 305-8506 Japan 2Seikagaku Biobusiness Corporation Tokyo Japan and laboratory for Immunopharmacology of Microbial Products School of Pharmacy Tokyo University of Pharmacy and Life Science Japan Email Ken-ichiro Inoue - Hirohisa Takano - htakano@ Eiko Koike - ekoike@ Rie Yanagisawa - yanagi@ Toshio Oda - Hiroshi Tamura - Yoshiyuki Adachi - adachi@ Ken-ichi Ishibashi - ishiken@ Naohito Ohno - ohnonao@ Corresponding author Published 21 July 2009 Received 8 April 2009 Respiratory Research 2009 10 68 doi 1465-9921-10-68 Accepted 21 July 2009 This article is available from http content 10 1 68 2009 Inoue et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Although fungi have been implicated as initiating deteriorating factors for allergic asthma their contributing components have not been fully elucidated. We previously isolated soluble P-glucan from Candida albicans CSBG Ohno et al. 2007 . In the present study the effects of CSBG exposure on airway immunopathology in the presence or absence of other immunogenic allergen was investigated in vivo and their cellular mechanisms

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