tailieunhanh - Báo cáo y học: " Budesonide/formoterol as effective as prednisolone plus formoterol in acute exacerbations of COPD A double-blind, randomised, non-inferiority, parallel-group, multicentre study"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Budesonide/formoterol as effective as prednisolone plus formoterol in acute exacerbations of COPD A double-blind, randomised, non-inferiority, parallel-group, multicentre study. | Respiratory Research BioMed Central Research Budesonide formoterol as effective as prednisolone plus formoterol in acute exacerbations of COPD A double-blind randomised non-inferiority parallel-group multicentre study Bjorn Stăllberg1 Olof Selroos 2 Claus Vogelmeier3 Eva Andersson4 Tommy Ekstrom4 and Kjell Larsson5 Open Access Address Department of Public Health and Caring Sciences Family Medicine and Clinical Epidemiology Uppsala University Sweden 2Semeco Angelholm Sweden 3Universitătsklinikum Giessen and Marburg Marburg Germany 4AstraZeneca Sodertălje Sweden and 5Lung and Allergy Research Unit Karolinska Institutet Solna Sweden Email Bjorn Stăllberg - Olof Selroos - Claus Vogelmeier - Eva Andersson - Tommy Ekstrom - Kjell Larsson - Corresponding author Published 19 February 2009 Received I September 2008 Respiratory Research 2009 10 11 doi 1465-9921-10-11 Accepted 19 February 2009 This article is available from http content I0 I II 2009 Stăllberg et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Oral corticosteroids and inhaled bronchodilators with or without antibiotics represent standard treatment of COPD exacerbations of moderate severity. Frequent courses of oral steroids may be a safety issue. We wanted to evaluate in an out-patient setting whether a 2-week course of inhaled budesonide formoterol would be equally effective for treatment of acute COPD exacerbations as standard therapy in patients judged by the investigator not to require hospitalisation. Methods This was a double-blind .

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