tailieunhanh - Báo cáo y học: " Prevention of elastase-induced emphysema in placenta growth factor knock-out mice"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Prevention of elastase-induced emphysema in placenta growth factor knock-out mice. | Respiratory Research BioMed Central Research Prevention of elastase-induced emphysema in placenta growth factor knock-out mice Shih Lung Cheng1 2 3 Hao Chien Wang3 Chong Jen Yu 3 Po Nien Tsao4 Peter Carmeliet5 6 Shi Jung Cheng7 and Pan Chyr Yang3 Address Department of Internal Medicine Far Eastern Memorial Hospital Taiwan 2Department of Chemical Engineering and Materials Science Yuan-Ze University Taiwan 3Department of Internal Medicine National Taiwan University Hospital Taiwan 4Department of Pediatrics National Taiwan University Hospital Taiwan 5Vesalius Research Center VIB 3000 Leuven Belgium 6Vesalius Research Center . Leuven 3000 Leuven Belgium and 7Division of Oral and Maxillofacial Surgery Department of Dentistry National Taiwan University Hospital Taipei Taiwan Email Shih Lung Cheng - ntuhwyh61@ Hao Chien Wang - haochienwang@ Chong Jen Yu - jefferycjyu@ Po Nien Tsao - tsaopn@ Peter Carmeliet - Shi Jung Cheng - sjcheng56@ Pan Chyr Yang - pcyang@ Corresponding author Open Access Published 23 November 2009 Received 14 July 2009 Accepted 23 November 2009 Respiratory Research 2009 10 115 doi 1465-9921-10-115 This article is available from http content 10 1 1 15 2009 Cheng et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Although both animal and human studies suggested the association between placenta growth factor PlGF and chronic obstructive pulmonary disease COPD especially lung emphysema the role of PlGF in the pathogenesis of emphysema remains to be clarified. This study hypothesizes that blocking PlGF prevents the development of emphysema. Methods Pulmonary .