tailieunhanh - Báo cáo y học: "Neurogenic diabetes insipidus presenting in a patient with subacute liver failure: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Neurogenic diabetes insipidus presenting in a patient with subacute liver failure: a case report. | Shankar Hari et al. Journal of Medical Case Reports 2010 4 232 http content 4 1 232 jAl JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access Neurogenic diabetes insipidus presenting in a patient with subacute liver failure a case report 1 1 21 2 1 Manu Shankar Hari Anthony K Parsons Andy K Burroughs Steve Shaw James OBeirne Banwari Agarwal Abstract Introduction To the best of our knowledge this is the first report in the literature of development of neurogenic diabetes insipidus in a patient with subacute liver failure. Case presentation A 25-year-old man presented with subacute liver failure. While awaiting a liver transplant the patient developed cerebral edema which resulted in neurogenic diabetes insipidus secondary to cerebral edema. The patient died before the liver transplantation could be carried out. Conclusion Neurogenic diabetes insipidus is well recognized in the neurosurgical population as a consequence of cerebral edema and increased intracranial pressure both of which occur commonly in patients with subacute liver failure. Introduction Cerebral edema occurs in patients presenting with fulminant liver failure resulting in increased intracranial pressure ICP . The incidence and severity of cerebral edema increases as the onset of liver failure becomes rapid. It occurs in up to 80 of patients with acute and hyperacute fulminant liver failure but less frequently 20 in those with subacute fulminant liver failure. There is a significant association between the presence of cerebral edema and the development of central diabetes insipidus in patients with traumatic brain injury 1 and in postoperative neurosurgical patients. We present a case of neurogenic diabetes insipidus that developed during the course of subacute fulminant liver failure. Case presentation A 25-year-old Nigerian man was admitted to our hospital s intensive care unit ICU after emergency tracheal intubation and ventilation for worsening encephalopathy and a