tailieunhanh - báo cáo khoa học: " Allergic bronchopulmonary aspergillosis with coexistant aspergilloma: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Allergic bronchopulmonary aspergillosis with coexistant aspergilloma: a case report | Kern and Lopert Journal of Medical Case Reports 2010 4 309 http content 4 1 309 jAg JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access Allergic bronchopulmonary aspergillosis with coexistant aspergilloma a case report Izidor Kern1 Anton Lopert2 Abstract Introduction The coexistence of allergic bronchopulmonary aspergillosis and aspergilloma is rare. Case presentation We present the case of a 56-year-old Caucasian man who worked as a farmer with infiltrates in the right lower and middle lung lobes partial consolidation of the middle lobe and with previous diagnosis of chronic obstructive bronchitis. Evaluation of our patient led to the diagnosis of allergic bronchopulmonary aspergillosis with coexistent aspergilloma in the right lower lobe. He was treated with oral methylprednisolone and itraconazole. At the five-year follow-up he is without any sign of recurrence. Conclusion Aspergillus infection after the inhalation of spores in the form of a hypersensitivity reaction and saprophytic colonization can be coexistent. Introduction Allergic bronchopulmonary aspergillosis ABPA is a complex hypersensitivity reaction in patients with asthma which occurs when bronchi are colonized by the fungus Aspergillus most often Aspergillus fumigatus. The disease is characterized by type I and type III hypersensitivity reactions. The incidence may be as high as 6 of patients with asthma 1 . Repeated episodes of bronchial obstruction inflammation and mucoid impaction can lead to bronchiectasis fibrosis and respiratory compromise. Aspergilloma is a saprophytic growth of fungus usually A. fumigatus in the lumen of an existing cavity which does not invade the tissue. Fungus ball formation has been observed in an old tuberculosis cavity bronchiectasis abscess or in a congenital cyst. We present a case of the coexistence of ABPA and aspergilloma. A patient with ABPA developed a cavitary pulmonary lesion with characteristic radiological appearances of .