tailieunhanh - báo cáo khoa học: " Urethral metastasis from non-seminomatous germ cell tumor: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Urethral metastasis from non-seminomatous germ cell tumor: a case report | Agarwal et al. Journal of Medical Case Reports 2011 5 12 http content 5 1 12 WV journalof medical l rCASE REPORTS CASE REPORT Open Access Urethral metastasis from non-seminomatous germ cell tumor a case report 1 2 3 1 1 Vijay Agarwal Tze Wah Sameer Chilka Johnathan Joffe Dan Stark Abstract Introduction We present a case of nonseminomatous germ cell tumor of the testes with acute urinary retention secondary to urethral metastasis. This presentation and similar cases of urethral metastasis from this tumor have not been reported previously. Case presentation A 35-year-old Caucasian man presented to hospital with a history of acute urinary retention. On examination he was found to have right testicular enlargement with raised p-human chorionic gonadotrophin serum a-fetoprotein and lactate dehydrogenase levels. He underwent radical left inguinal orchidectomy and histology confirmed a nonseminomatous germ cell tumor of the testes. Cystoscopy carried out due to urinary retention showed penile metastasis and the biopsy confirmed metastatic malignant undifferentiated teratoma. Staging computed tomography scan and magnetic resonance imaging of the pelvis showed pulmonary pelvic nodal ischial and penile metastasis. The diagnosis of the International Germ Cell Cancer Collaborative Group of poor prognosis metastatic nonseminomatous germ cell tumor was made following which he received four cycles of bleomycin etoposide and cisplatin chemotherapy with curative intent. He had a complete marker and an excellent radiological response. He is currently under follow up. Conclusion The unusual presentation of lymphovascular spread in this case of nonseminomatous germ cell tumor highlights the need to include routine pelvic imaging in the assessment and follow up of testicular cancer. Introduction We report the case of a Caucasian man who presented with acute urinary retention and was found to have urethral metastasis from a nonseminomatous germ cell tumor. .

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