tailieunhanh - báo cáo khoa học: " Oncocytic carcinoma of the parotid gland with late cervical lymph node metastases: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Oncocytic carcinoma of the parotid gland with late cervical lymph node metastases: a case report | Gallego et al. Journal of Medical Case Reports 2011 5 11 http content 5 1 11 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access Oncocytic carcinoma of the parotid gland with late cervical lymph node metastases a case report 1 I f s 1 2 1 Lorena Gallego Luis García-Consuegra Eduardo Fuente Nicolas Calvo Luis Junquera Abstract Introduction Oncocytic carcinoma is a rare proliferation of cytomorphologically malignant oncocytes mainly found in glandular tissue accounting for of all epithelial salivary gland malignancies and of all epithelial salivary gland tumors. Case presentation We report a case of oncocytic carcinoma arising in the parotid gland of a 65-year-old Caucasian man. Our patient initially underwent left superficial parotidectomy including the removal of the mass. A close follow-up was made and four years after first surgery cervical lymph node metastases were confirmed. Therefore a complete parotidectomy and radical neck dissections were performed. There were no complications and no sign of recurrence after six months of follow-up. Conclusion Oncocytic carcinoma is an extremely rare malignancy in the salivary glands. Prophylactic neck dissection may be indicated for tumors larger than 2 cm in diameter our patient s tumor was cm at its greatest diameter . The clinical course of our patient with the appearance of cervical lymph node metastases after four years of follow-up supports this approach. Further investigation of the prognosis and correct treatment of patients with oncocytic carcinoma are required as more cases are reported. Introduction Oncocytic carcinoma OC is an unusual proliferation of cytomorphologically malignant oncocytes and adenocar-cinomatous architecture phenotypes mainly found in glandular tissue 1 . The terms oncocytic carcinoma oncocytic adenocarcinoma malignant oncocytoma and malignant oxyphilic adenoma are synonymous. Its malignant nature is distinguished from oncocytoma by abnormal .