tailieunhanh - Crosstalk between SET7/9-dependent methylation and ARTD1-mediated ADP-ribosylation of histone H1.4

Histones are nuclear proteins that package and order the DNA into nucleosomes [1]. Five major families of histones exist: H1 (H5), H2A, H2B, H3, and H4. Two copies of the core histones H2A, H2B, H3 and H4 form the octameric nucleosome core particles [2]. Unlike the other histones, only one copy of the linker histone H1 is present and stabilizes the DNA, which is wrapped around the core nucleosome [3]. Linker histones bind to both the nucleosome and the linker DNA region (approximately 20 to 80 nucleotides in length) between nucleosomes. The interaction of H1 with the nucleosome and additional DNA stretches at the entry/exit of the. | Epigenetics Chromatin BioMed Central Vz The Open Access Publisher This Provisional PDF corresponds to the article as it appeared upon acceptance. Fully formatted PDF and full text HTML versions will be made available soon. Crosstalk between SET7 9-dependent methylation and ARTDI-mediated ADP-ribosylation of histone Epigenetics Chromatin 2013 6 1 doi 1756-8935-6-1 Ingrid Kassner Marc Barandun Monika Fey fey@ Florian Rosenthal Michael O Hottiger hottiger@ ISSN 1756-8935 Article type Research Submission date 12 December 2012 Acceptance date 14 December 2012 Publication date 5 January 2013 Article URL http content 6 1 1 This peer-reviewed article can be downloaded printed and distributed freely for any purposes see copyright notice below . Articles in Epigenetics Chromatin are listed in PubMed and archived at PubMed Central. For information about publishing your research in Epigenetics Chromatin or any BioMed Central journal go to http authors instructions For information about other BioMed Central publications go to http 2013 Kassner et al. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Crosstalk between SET7 9-dependent methylation and ARTD1-mediated ADP-ribosylation of histone Ingrid Kassner1 2 Email Marc Barandun1 Email Monika Fey1 Email fey@ Florian Rosenthal1 2 Email Michael O Hottiger1 Corresponding author Email hottiger@ 1 Institute of Veterinary Biochemistry and Molecular Biology University of Zurich Winterthurerstrasse 190 Zurich 8057 .