tailieunhanh - báo cáo khoa học: "An 82-year-old Caucasian man with a ductal prostate adenocarcinoma with unusual cystoscopic appearance: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: An 82-year-old Caucasian man with a ductal prostate adenocarcinoma with unusual cystoscopic appearance: a case report | Sfoungaristos et al. Journal of Medical Case Reports 2011 5 4 http content 5 1 4 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access An 82-year-old Caucasian man with a ductal prostate adenocarcinoma with unusual cystoscopic appearance a case report 1 2 2 13 Stavros Sfoungaristos loannis S Katafigiotis Stavros I Tyritzis Adamantios Kavouras Panagiotis Kanatas Anastasios Petas4 Abstract Introduction Ductal adenocarcinoma is a rare variety of the common acinar adenocarcinoma. It usually presents with refractory symptoms and during cystoscopy it is seen as an exophytic lesion at the area of the verumontanum. Case presentation An 82-year-old Caucasian man was diagnosed with ductal adenocarcinoma of the prostate after undergoing transurethral resection of the prostate for urinary retention. Immunohistochemistry confirmed the nature of the tumor. The patient was treated with triptorelin mg once month and bicalutamide 50 mg 1 X 1. The serum prostate-specific antigen at three six and 12 months after transurethral resection of the prostate was ng ml. The patient remains asymptomatic and he entered a six-month follow-up protocol. Conclusion Ductal adenocarcinoma often involves the central ducts of the gland and may present as an exophytic papillary lesion in the prostatic urethra. This is why it usually presents with refractory symptoms. The outcome for men with prostatic ductal adenocarcinoma is in most studies worse than the outcome for men with prostatic acinar adenocarcinoma. Aggressive management is indicated even with low-volume metastatic disease. Introduction Ductal carcinoma of the prostate was originally identified by Melicow and Pachter in 1967. Thought initially to be a neoplastic proliferation of remnant paramesonephric tissue it was given the name endometrioid carcinoma. More extensive pathologic analysis including ultrastruc-tural studies determined that these tumors however originate from the prostate and are now more