tailieunhanh - Báo cáo y học: "Individual and occupational risk factors for knee osteoarthritis: results of a case-control study in Germany"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Individual and occupational risk factors for knee osteoarthritis: results of a case-control study in Germany. | Klussmann et al. Arthritis Research Therapy 2010 12 R88 http content 12 3 R88 RESEARCH ARTICLE Open Access Individual and occupational risk factors for knee osteoarthritis results of a case-control study in Germany André Klussmann 1 Hansjurgen Gebhardt1 Matthias Nubling2 Falk Liebers3 Emilio Quirós Perea4 Wolfgang Cordier4 Lars V von Engelhardt5 Markus Schubert5 Andreas Dávid5 Bertil Bouillon6 and Monika A Rieger7 8 Abstract Introduction A number of occupational risk factors are discussed in relation to the development and progress of knee joint diseases for example working in a kneeling or squatting posture lifting and carrying heavy weights . Besides the occupational factors a number of individual risk factors are important. The distinction between work-related and other factors is crucial in assessing the risk and in deriving preventive measures in occupational health. Methods In a case-control study patients with and without symptomatic knee osteoarthritis OA were questioned by means of a standardised questionnaire complemented by a semi-standardised interview. Controls were matched and assigned to the cases by gender and age. Conditional logistic regression was used in analysing data. Results In total 739 cases and 571 controls were included in the study. In women and men several individual and occupational predictors for knee OA could be described obesity odds ratio OR up to in women and up to in men kneeling squatting women OR 8 934 hours life men 574 to 12 244 hours life 12 244 hours life genetic predisposition women OR men OR and sports with a risk of unapparent trauma women OR 1 440 hours life men 3 232 hours life . In women malalignment of the knee OR pain in the knee already in childhood OR and the daily lifting and carrying of loads 1 088 tons life OR were related to an increased OR sitting and smoking led to a reduced OR. Conclusions The results support a .