tailieunhanh - Báo cáo y học: "Phytalgic®, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Phytalgic®, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial. | Available online http content 11 6 R192 Research article Phytalgic a food supplement vs placebo in patients with osteoarthritis of the knee or hip a randomised double-blind placebo-controlled clinical trial Alain Jacquet1 Pierre-Olivier Girodet1 2 3 Antoine Pariente1 2 3 Karelle Forest1 Laurent Mallet4 and Nicholas Moore1 2 3 Department of Pharmacology University of Bordeaux 146 rue Léo Saignat 33076 Bordeaux France 2CHU de Bordeaux 12 rue Dabernat 33404 Talence France 3Centre d Investigation Clinique INSERM CIC0005 146 rue Léo Saignat 33076 Bordeaux France 4Phythea 13 Rue Elsa Triolet 77176 Savigny France Corresponding author Nicholas Moore Received 8 Jul 2009 Revisions requested 9 Sep 2009 Revisions received 27 Nov 2009 Accepted 16 Dec 2009 Published 16 Dec 2009 Arthritis Research Therapy 2009 11 R192 doi ar2891 This article is online at http content 11 6 R192 2009 Jacquet et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction The medicinal treatment of osteoarthritis OA is mostly symptomatic to relieve pain and incapacity with analgesics and non-steroidal anti-inflammatory drugs NSAIDs drugs with well-known risks. Complementary medicines might reduce the symptoms of OA and decrease the need for NSAIDs. This study tested the effects of a food supplement Phytalgic on pain and function in patients with osteoarthritis and their use of analgesic and NSAIDs. Methods A randomized double-blind parallel-groups clinical trial compared Phytalgic fish-oil vitamin E Urtica dioica to a placebo for three months in 81 patients with OA of the knee or hip using NSAIDs and or analgesics regularly. The main outcome

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