tailieunhanh - Báo cáo y học: " Decline in air pollution and change in prevalence in respiratory symptoms and chronic obstructive pulmonary disease in elderly women"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: Decline in air pollution and change in prevalence in respiratory symptoms and chronic obstructive pulmonary disease in elderly women. | Schikowski et al. Respiratory Research 2010 11 113 http content 11 1 113 RESPIRATORY RESEARCH RESEARCH Open Access Decline in air pollution and change in prevalence in respiratory symptoms and chronic obstructive pulmonary disease in elderly women 1 1 1 4 4 Tamara Schikowski Ulrich Ranft Dorothee Sugiri Andrea Vierkotter Thomas Bruning Volker Harth Ursula Kramer1 Abstract Background While adverse effects of exposure to air pollutants on respiratory health are well studied little is known about the effect of a reduction in air pollutants on chronic respiratory symptoms and diseases. We investigated whether different declines in air pollution levels in industrialised and rural areas in Germany were associated with changes in respiratory health over a period of about 20 years. Methods We used data from the SALIA cohort study in Germany Study on the influence of Air pollution on Lung function inflammation and Aging to assess the association between the prevalence of chronic obstructive pulmonary disease COPD and chronic respiratory symptoms and the decline in air pollution exposure. In 19851994 4874 women aged 55-years took part in the baseline investigation. Of these 2116 participated in a questionnaire follow-up in 2006 and in a subgroup of 402 women lung function was tested in 2008-2009. Generalized estimating equation GEE models were used to estimate the effect of a reduction in air pollution on respiratory symptoms and diseases. Results Ambient air concentrations of particulate matter with aerodynamic size 10 pm PM10 declined in average by 20 pg m3. Prevalence of chronic cough with phlegm production and mild COPD at baseline investigation compared to follow-up was vs. and vs. respectively. A steeper decline of PM10 was observed in the industrialized areas in comparison to the rural area this was associated with a weaker increase in prevalence of respiratory symptoms and COPD. Among women who never smoked the .