tailieunhanh - Báo cáo y học: "Efficacy of a progressive walking program and glucosamine sulphate supplementation on osteoarthritic symptoms of the hip and knee: a feasibility trial"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Efficacy of a progressive walking program and glucosamine sulphate supplementation on osteoarthritic symptoms of the hip and knee: a feasibility trial. | Ng et al. Arthritis Research Therapy 2010 12 R25 http content 12 1 R25 RESEARCH ARTICLE Open Access Efficacy of a progressive walking program and glucosamine sulphate supplementation on osteoarthritic symptoms of the hip and knee a feasibility trial Norman TM Ng1 Kristiann C Heesch1 2 Wendy J Brown1 Abstract Introduction Management of osteoarthritis OA includes the use of non-pharmacological and pharmacological therapies. Although walking is commonly recommended for reducing pain and increasing physical function in people with OA glucosamine sulphate has also been used to alleviate pain and slow the progression of OA. This study evaluated the effects of a progressive walking program and glucosamine sulphate intake on OA symptoms and physical activity participation in people with mild to moderate hip or knee OA. Methods Thirty-six low active participants aged 42 to 73 years were provided with 1500 mg glucosamine sulphate per day for 6 weeks after which they began a 12-week progressive walking program while continuing to take glucosamine. They were randomized to walk 3 or 5 days per week and given a pedometer to monitor step counts. For both groups step level of walking was gradually increased to 3000 steps day during the first 6 weeks of walking and to 6000 steps day for the next 6 weeks. Primary outcomes included physical activity levels physical function self-paced step test and the WOMAC Osteoarthritis Index for pain stiffness and physical function. Assessments were conducted at baseline and at 6- 12- 18- and 24-week follow-ups. The Mann Whitney Test was used to examine differences in outcome measures between groups at each assessment and the Wilcoxon Signed Ranks Test was used to examine differences in outcome measures between assessments. Results During the first 6 weeks of the study glucosamine supplementation only physical activity levels physical function and total WOMAC scores improved P . Between the start of the walking program