tailieunhanh - Risk Factors Affecting the Development of Tuberculosis Infection and Disease in Household Contacts of Patients with Pulmonary Tuberculosis

Tuberculosis Dispensaries in Turkey do the follow up of the treatment of tuberculosis patients. Tuberculosis Dispensaries are present nearly in all regions the country. In these dispensaries chest x rays are obtained for patients who has respiratory complaints and for patients who applied for health report to start a new job. The sputum examination and culture are done in patients tuberculosis suspected due to clinical and radiological findings. The patients who needed further evaluation were sent to chest disease hospitals. The physical examinations, investigations and follow up of the tuberculosis contacts are also done in these dispensaries. In this study we aimed to determine the frequency of TB development in household contacts. | ORIGINAL ARTICLE Turkish Respiratory Journal 2008 9 1 34-7 Tuberculosis Risk Factors Affecting the Development of Tuberculosis Infection and Disease in Household Contacts of Patients with Pulmonary Tuberculosis Fahrettin Talay1 fienol Kumbetli2 1Abant Izzet Baysal University Izzet Baysal Faculty of Medicine Department of Chest Disease Bolu Turkey 2Eyup Tuberculosis Dispensary Istanbul Turkey Abstract Objective The aim of this study was to investigate the incidence of tuberculosis and factors effecting development of tuberculosis in household contact individuals with pulmonary tuberculosis patients. Methods The total number of recorded in-house contacts of 153 pulmonary tuberculosis patients was 625 patients came to control and were documented for treatment and follow up in Istanbul Eyup Tuberculosis Dispensary between January 2001 and December 2002. Results Tuberculosis was detected in 35 household contacts. The incidence of tuberculosis in household contacts was found to be related with the presence of cavity in tuberculosis patient in patients with cavity and in patients without cavity p . Mean TST positivity rate of household contacts under 15 years old was higher in cases whose index case had cavity and positive sputum AFB than cases whose index case had no cavity and negative sputum AFB p . Conclusion These household contacts with pulmonary tuberculosis patients having cavity and smear positive are the most risky group for tuberculosis contamination and are the easiest group to detect tuberculosis. Close follow up of household contacts of such patients for tuberculosis is important for tuberculosis Key words Pulmonary tuberculosis household contact examination risk factor Received Accepted INTRODUCTION Although tuberculosis TB is a treatable disease every day 5 thousand people die because of this disease 1 . More than 90 of TB cases and deaths occur in developing countries and 75 of these cases are between 15 and 54

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