tailieunhanh - Cytologic Detection of Urothelial Lesions - part 6

Cao Urothelial rửa bàng quang Ung thư biểu mô-Lớp: Một nhóm các tế bào ác tính cao cấp urothelial được nhìn thấy. Một số tế bào ác tính đã nhấn chìm các tế bào ác tính và hiển thị được đánh dấu hyperchromasia hạt nhân. Vacuolization tế bào chất, mặc dù không nổi bật, | 90 3. Grading Urothelial Neoplasms Figure . High Grade Urothelial Carcinoma bladder washing A cluster of malignant high grade urothelial cells is seen. Some malignant cells have engulfed other malignant cells and show marked nuclear hyper-chromasia. Cytoplasmic vacuolization although not prominent may be seen in high grade urothelial carcinomas. In this case there is not marked nuclear overlap. 600x High Grade Urothelial Carcinoma 91 Figure . High Grade Urothelial Carcinoma bladder washing In this photomicrograph numerous malignant cells are seen. The cells exhibit high nuclear to cytoplasmic ratios nuclear hyperchromasia and nuclear membrane irregularities. The nuclear membrane appears thick in many instances. 600x 92 3. Grading Urothelial Neoplasms Figure . High Grade Urothelial Carcinoma voided urine Degenerated malignant cells are seen admixed with benign squamous cells. Although the nuclei are small and slightly degenerated the nuclear membranes are markedly thickened and irregular. Often degeneration may limit interpretation of high grade urothelial carcinoma. 600x