tailieunhanh - báo cáo hóa học:" The longitudinal link between visual acuity and health-related quality of life in patients with diabetic retinopathy

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : The longitudinal link between visual acuity and health-related quality of life in patients with diabetic retinopathy | Health and Quality of Life Outcomes BioMed Central Open Access The longitudinal link between visual acuity and health-related quality of life in patients with diabetic retinopathy Louis S Matza 1 Matthew D Rousculp2 Karen Malley3 Kristina S Boye4 and Alan Oglesby2 Address 1Center for Health Outcomes Research United BioSource Corporation 7101 Wisconsin Avenue Suite 600 Bethesda MD 20814 USA 2Eli Lilly Company Indianapolis IN USA 3Malley Research Programming Inc Rockville MD USA and 4Eli Lilly Company Indianapolis IN USA Email Louis S Matza - Matthew D Rousculp - rousculpm@ Karen Malley - kgmalley@ Kristina S Boye - boye_kristina_secnik@ Alan Oglesby - aoglesby@ Corresponding author Published 7 November 2008 Received 15 April 2008 Health and Quality of Life Outcomes 2008 6 95 doi 1477-7525-6-95 Accepted 7 November 2008 This article is available from http content 6 1 95 2008 Matza et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background This study characterized the degree of change in health-related quality of life HRQL associated with change in visual acuity among patients with diabetic retinopathy. Methods Data are from a randomized placebo-controlled trial of ruboxistaurin for vision loss in patients with diabetic retinopathy. Visual acuity was quantified as letters on the ETDRS visual acuity chart. HRQL was assessed with the 25-Item Visual Function Questionnaire VFQ-25 and the SF-36. Patients were categorized into groups based on visual acuity change from baseline to month 18. HRQL change of these groups was compared using general linear models. Regression analyses examined visual acuity change defined .