tailieunhanh - báo cáo hóa học:" The validity and responsiveness of three quality of life measures in the assessment of psoriasis patients: results of a phase II study"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : The validity and responsiveness of three quality of life measures in the assessment of psoriasis patients: results of a phase II study | Health and Quality of Life Outcomes BioMed Central Open Access The validity and responsiveness of three quality of life measures in the assessment of psoriasis patients results of a phase II study Richard Shikiar1 Mary Kaye Willian2 Martin M Okun3 Christine S Thompson1 and Dennis A Revicki 1 Address 1Center for Health Outcomes Research United BioSource Corporation Bethesda MD USA 2Global Health Economics and Outcomes Research Abbott Laboratories Abbott Park IL USA and 3Abbott Immunology Abbott Laboratories Abbott Park IL USA Email Richard Shikiar - Mary Kaye Willian - Martin M Okun - Christine S Thompson - Dennis A Revicki - Corresponding author Published 27 September 2006 Received 24 August 2006 7 77. JT. .mz. 7777 A -71 J 177 I 177771 A- - -77-7 7- A 7 1 Accepted 27 September 2006 Health and Quality of Life Outcomes 2006 4 71 doi 1477-7525-4-71 This article is available from http content 4 1 71 2006 Shikiar et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Patient-reported outcome PROs measures are being used more frequently in investigational studies of treatments for moderate to severe plaque psoriasis. The objective of this study was to examine the relationships among the Dermatology Life Quality Index DLQI the Short Form 36 SF-36 and the EuroQOL 5D EQ-5D and to assess their validity responsiveness and estimates of minimum important differences. Methods A Phase II randomized double-blind parallel group placebo-controlled multi-center .

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