tailieunhanh - báo cáo hóa học:" Anxiety and depression in association with morbid obesity: changes with improved physical health after duodenal switch"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : Anxiety and depression in association with morbid obesity: changes with improved physical health after duodenal switch | Andersen et al. Health and Quality of Life Outcomes 2010 8 52 http content 8 1 52 I HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access Anxiety and depression in association with morbid obesity changes with improved physical health after duodenal switch John Roger Andersen 1 4 Anny Aasprang1 Per Bergsholm2 Nils Sletteskog3 Villy Vâge3 and Gerd Karin Natvig4 Abstract Background Patients with morbid obesity have an increased risk for anxiety and depression. The duodenal switch is perhaps the most effective obesity surgery procedure for inducing weight loss. However to our knowledge data on symptoms of anxiety and depression after the duodenal switch are lacking. Furthermore it has been hypothesized that self-reported physical health is the major predictor of symptoms of depression in patients with morbid obesity. We therefore investigated the symptoms of anxiety and depression before and after the duodenal switch procedure and whether post-operative changes in self-reported physical health were predictive of changes in these symptoms. Methods Data were assessed before surgery n 50 and one n 47 and two n 44 years afterwards. Symptoms of anxiety and depression were assessed by the Hospital Anxiety and Depression Scale and self-reported physical health was assessed by the Short-Form 36 questionnaire. Linear mixed effect models were used to investigate changes in the symptoms of anxiety and depression. Correlation and linear multiple regression analyses were used to study whether changes in self-reported physical health were predictive of post-operative changes in the symptoms of anxiety and depression. Results The symptom burden of anxiety and depression were high before surgery but were normalized one and two years afterwards P . The degree of improvement in self-reported physical health was associated with statistically significant reductions in the symptoms of anxiety P and depression P . Conclusions The novelty of this study is .