tailieunhanh - báo cáo hóa học:" Validation of the "World Health Organization Disability Assessment Schedule, WHODAS-2" in patients with chronic diseases"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : Validation of the "World Health Organization Disability Assessment Schedule, WHODAS-2" in patients with chronic diseases | Garin et al. Health and Quality of Life Outcomes 2010 8 51 http content 8 1 51 I HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access Validation of the World Health Organization Disability Assessment Schedule WHODAS-2 in patients with chronic diseases Olatz Garin 1 2 Jose Luis Ayuso-Mateos3 Josué Almansa1 Marta Nieto3 Somnath Chatterji4 Gemma Vilagut1 2 Jordi Alonso1 2 Alarcos Cieza5 Olga Svetskova6 Helena Burger7 Vittorio Racca8 Carlo Francescutti9 Eduard Vieta10 Nenad Kostanjsek4 Alberto Raggi11 Matilde Leonardi11 Montse Ferrer 1 2 12 for the MHADIE consortium Abstract Background The WHODAS-2 is a disability assessment instrument based on the conceptual framework of the International Classification of Functioning Disability and Health ICF . It provides a global measure of disability and 7 domain-specific scores. The aim of this study was to assess WHODAS-2 conceptual model and metric properties in a set of chronic and prevalent clinical conditions accounting for a wide scope of disability in Europe. Methods 1 119 patients with one of 13 chronic conditions were recruited in 7 European centres. Participants were clinically evaluated and administered the WHODAS-2 and the SF-36 at baseline 6 weeks and 3 months of follow-up. The latent structure was explored and confirmed by factor analysis FA . Reliability was assessed in terms of internal consistency Cronbach s alpha and reproducibility intra-class correlation coefficients ICC . Construct validity was evaluated by correlating the WHODAS-2 and SF-36 domains and comparing known groups based on the clinical-severity and work status. Effect size ES coefficient was used to assess responsiveness. To assess reproducibility and responsiveness subsamples of stable at 6 weeks and improved after 3 moths patients were defined respectively according to changes in their clinical-severity. Results The satisfactory FA goodness of fit indexes confirmed a second order factor structure with 7 dimensions and a global .