tailieunhanh - báo cáo hóa học:" Quality of life and hormone use: new validation results of MRS scale"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : Quality of life and hormone use: new validation results of MRS scale | BioMed Central Health and Quality of Life Outcomes Research Open Access Quality of life and hormone use new validation results of MRS scale Jurgen Dinger1 Thomas Zimmermann2 Lothar AJ Heinemann 1 and Diana Stoehr3 Address 1Center for Epidemiology Health Research Berlin Invalidenstr. 115 10115 Berlin Germany 2Jenapharm Medical Affairs Gynecology Otto-Schott-Str. 15 07745 Jena Germany and 3University of Wuerzburg Chair of Statistics Am Hubland 97074 Wurzburg Germany Email Jurgen Dinger - dinger@ Thomas Zimmermann - Lothar AJ Heinemann - heinemann@ Diana Stoehr - Corresponding author Published 31 May 2006 Received 23 January 2006 Health and Quality of Life Outcomes 2006 4 32 doi 1477-7525-4-32 Accepted 31 May 2006 This article is available from http content 4 1 32 2006 Dinger et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The Menopause Rating Scale is a health-related Quality of Life scale developed in the early 1990s and step-by-step validated since then. Recently the MRS scale was validated as outcomes measure for hormone therapy. The suspicion however was expressed that the data were too optimistic due to methodological problems of the study. A new study became available to check how founded this suspicion was. Method An open post-marketing study of 3282 women with pre- and post- treatment data of the selfadministered version of the MRS scale was analyzed to evaluate the capacity of the scale to detect hormone treatment related effects with the MRS scale. The main results were then compared with the old study where the interview-based version of the MRS scale was used. Results The

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