tailieunhanh - báo cáo hóa học: " Spinsterhood and its impact on disease features in women with rheumatoid arthritis"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : Spinsterhood and its impact on disease features in women with rheumatoid arthritis | Ibn Yacoub et al. Health and Quality of Life Outcomes 2011 9 58 http content 9 1 58 HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access Spinsterhood and its impact on disease features in women with rheumatoid arthritis Yousra Ibn Yacoub Bouchra Amine Assia Laatiris and Najia Hajjaj-Hassouni Abstract Objective To evaluate the impact of spinsterhood on disease characteristics and quality of life QoL in Moroccan women with rheumatoid arthritis RA . Methods 185 women with RA were recruited in this study. Marital status was specified as follow 1. Spinsterhood never-married woman aged 38 or over 2. Distressed marriage 3. Nondistressed marriage and 4. Divorced or widowed. Marital distress was assessed by a self-report concerning coping efficacy and burden caring of husbands. Assessment criteria included the evaluation of age at onset years diagnosis delay months disease duration years disease activity evaluated by physical examination biological inflammatory tests and disease activity score DAS 28 pain intensity measured with a visual analogue scale VAS and radiographic damage evaluated by the Sharp s method as modified by van der Heijde . Treatments doses and duration were specified. The Health Assessment Questionnaire HAQ was used to evaluate functional disability. QoL was measured using the Arabic version of the generic instrument SF-36. Results In our data spinsterhood was detected in 42 patients vs. 88 with distressed marriage 28 with nondistressed marriage and 27 divorced or widowed. Comparing the 4 groups we found that QoL in never-married women was damaged in a significant way comparing to the other groups. Mental as well as physical aspects were affected. Also we found that spinsterhood was associated to an early age at onset p pain intensity p clinical p and biological disease activity C-reactive protein p and functional disability p . Logistic regression analysis revealed a significant .