tailieunhanh - Báo cáo y học: "A sleeping phantom leg awakened following hemicolectomy, thrombosis, and chemotherapy: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: A sleeping phantom leg awakened following hemicolectomy, thrombosis, and chemotherapy: a case report. | Giummarra et al. Journal of Medical Case Reports 2011 5 203 http content 5 1 203 JOURNALOF medical Ur Case REPORTS CASE REPORT Open Access A sleeping phantom leg awakened following hemicolectomy thrombosis and chemotherapy a case report Melita J Giummarra 1 John L Bradshaw1 Michael ER Nicholls2 Nellie Georgiou-Karistianis1 and Stephen J Gibson3 4 Abstract Introduction We describe the case of a patient who experienced phantom pain that began 42 years after right above-the-knee amputation. Immediately prior to phantom pain onset this long-term amputee had experienced in rapid succession cancer hemicolectomy chemotherapy and thrombotic occlusion. Very little has been published to date on the association between chemotherapy and exacerbation of neuropathic pain in amputees let alone the phenomenon of bringing about pain in amputees who have been pain-free for many decades. While this patient presented with a unique profile following a rare sequence of medical events his case should be recognized considering the frequent co-occurrence of osteomyelitis chemotherapy and amputation. Case presentation A 68-year-old Australian Caucasian man presented 42 years after right above-the-knee amputation with phantom pain immediately following hemicolectomy thrombotic occlusion in the amputated leg and chemotherapy treatment with leucovorin and 5-fluorouracil. He exhibited probable hyperalgesia with a reduced pinprick threshold and increased stump sensitivity indicating likely peripheral and central sensitization. Conclusion Our patient who had long-term nerve injury due to amputation together with recent ischemic nerve and tissue injury due to thrombosis exhibited likely chemotherapy-induced neuropathy. While he presented with unique treatment needs cases such as this one may actually be quite common considering that osteosarcoma can frequently lead to amputation and be followed by chemotherapy. The increased susceptibility of amputees to developing .