tailieunhanh - báo cáo khoa học: "Synthesis of three-dimensional calcium carbonate nanofibrous structure from eggshell using femtosecond laser ablation"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Synthesis of three-dimensional calcium carbonate nanofibrous structure from eggshell using femtosecond laser ablation | Tavangar et al. Journal of Nanobiotechnology 2011 9 1 http content 9 1 1 JOURNAL OF NANOBIOTECHNOLOGY RESEARCH Open Access Synthesis of three-dimensional calcium carbonate nanofibrous structure from eggshell using femtosecond laser ablation Amirhossein Tavangar1 Bo Tan2 Krishnan Venkatakrishnan1 Abstract Background Natural biomaterials from bone-like minerals derived from avian eggshells have been considered as promising bone substitutes owing to their biodegradability abundance and lower price in comparison with synthetic biomaterials. However cell adhesion to bulk biomaterials is poor and surface modifications are required to improve biomaterial-cell interaction. Three-dimensional 3D nanostructures are preferred to act as growth support platforms for bone and stem cells. Although there have been several studies on generating nanoparticles from eggshells no research has been reported on synthesizing 3D nanofibrous structures. Results In this study we propose a novel technique to synthesize 3D calcium carbonate interwoven nanofibrous platforms from eggshells using high repetition femtosecond laser irradiation. The eggshell waste is value engineered to calcium carbonate nanofibrous layer in a single step under ambient conditions. Our striking results demonstrate that by controlling the laser pulse repetition nanostructures with different nanofiber density can be achieved. This approach presents an important step towards synthesizing 3D interwoven nanofibrous platforms from natural biomaterials. Conclusion The synthesized 3D nanofibrous structures can promote biomaterial interfacial properties to improve cell-platform surface interaction and develop new functional biomaterials for a variety of biomedical applications. Background Autogenous bone has long been considered the ideal grafting material in bone reconstructive surgery owing to its osteogenic osteoinductive and osteoconductive properties 1 2 . However harvesting the autogenous bone