tailieunhanh - Báo cáo y học: "Dermal reaction and bigeminal premature ventricular contractions due to neostigmine: a case repor"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Dermal reaction and bigeminal premature ventricular contractions due to neostigmine: a case report. | Yousefshahi et al. Journal of Medical Case Reports 2011 5 83 http content 5 1 83 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access Dermal reaction and bigeminal premature ventricular contractions due to neostigmine a case report Fardin Yousefshahi1 Mohammad Anbarafshan2 Patricia Khashayar3 Abstract Introduction Neostigmine is a frequently used acetylcholinesterase inhibitor administered to reverse muscular relaxation caused by nondepolarizing neuromuscular relaxants in patients recovering from general anesthesia. Severe allergic reactions and urticaria are rarely reported following the use of neostigmine bromide and never with methylsulfate-containing drugs. In this case bigeminal premature ventricular contractions added to urticaria provides a warning about the possibility of a life-threatening situation. Case presentation We report the case of a 23-year-old Persian woman who presented with bigeminal premature ventricular contractions along with urticarial lesions on her arm and trunk as soon as she was administered neostigmine methylsulfate after undergoing a laparoscopy for ectopic pregnancy. Conclusion This case report could be of value not only for anesthesiologists who routinely use neostigmine but also for others who administer the pharmaceutical preparation in other situations. The report presents a rare case of drug reaction following neostigmine use. As a result one should consider any drug a probable cause of drug reaction. The preparation of resuscitative facilities therefore is necessary prior to the prescription of the medication. Introduction Neostigmine generally used in combination with bromide or methylsulfate is an acetylcholine esterase inhibitor prescribed mainly to reverse the effects of muscular relaxants at the end of operations performed with the patient under general anesthesia. The drug is also used in patients with myasthenia gravis and paralytic ileus 1-3 . Increased saliva nausea and vomiting abdominal

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