tailieunhanh - Báo cáo y học: "Treatment of stasis dermatitis using aminaphtone: Spindle cell oncocytoma of the adenohypophysis in a woman: a case report and review of the literature"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Treatment of stasis dermatitis using aminaphtone: Spindle cell oncocytoma of the adenohypophysis in a woman: a case report and review of the literature. | Mlika et al. Journal of Medical Case Reports 2011 5 64 http content 5 1 64 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access Spindle cell oncocytoma of the adenohypophysis in a woman a case report and review of the literature . 1 . . . 1 . _ . 1 . _ _ .0 . . . .0 _ . . 1 . __ 1 .1 M Mlika1 H Azouz1 I Chelly1 I Ben Said2 H Jemel2 S Haouet1 M Zitouna1 N Kchir1 Abstract Introduction Spindle cell oncocytoma of the adenohypophysis is a rare tumour recently reported by Roncaroli et al. in 2002. This tumour is considered a grade I tumour by the World Health Organization. Case presentation We describe what is to the best of our knowledge the 14th case of its kind in the literature. A 45-year-old African woman presented clinical and radiological findings related to a nonfunctioning pituitary adenoma. The diagnosis was made on the basis of histological and immunohistochemical findings. Conclusion The purpose of this work is to report a rare pituitary tumour and to describe its histological and immunohistochemical features which were characterized by the expression of thyroid transcription factor 1 antigen by tumour cells. This fact could support the theory of a possible common origin of these tumours in pituicytomas. In fact thyroid transcription factor 1 is considered to be a specific marker of pituicytes. Introduction Spindle cell oncocytoma SCO of the pituitary gland is a recently described entity which was recognized by the 2007 WHO Classification of Brain Tumours and considered a WHO grade I tumour 1 . It was initially described by Roncaroli et al. in 2002 2 and only 14 cases have been reported in the literature. The histogenesis and prognosis of these tumours remain uncertain and need to be documented more thoroughly in the literature. Our aim is to report a new case of SCO and to describe its histological and immunohistochemical features supporting the theory of a possible common origin with pituicytoma 2 . Case presentation We report