tailieunhanh - báo cáo hóa học:" Disability in activities of daily living, depression, and quality of life among older medical ICU survivors: a prospective cohort study"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : Disability in activities of daily living, depression, and quality of life among older medical ICU survivors: a prospective cohort study | Vest et al. Health and Quality of Life Outcomes 2011 9 9 http content 9 1 9 HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access Disability in activities of daily living depression and quality of life among older medical ICU survivors a prospective cohort study 1 2 2 3 Michael T Vest Terrence E Murphy Katy LB Araujo Margaret A Pisani Abstract Background Accurate measurement of quality of life in older ICU survivors is difficult but critical for understanding the long-term impact of our treatments. Activities of daily living ADLs are important components of functional status and more easily measured than quality of life QOL . We sought to determine the crosssectional associations between disability in ADLs and QOL as measured by version one of the Short Form 12-item Health Survey SF-12 at both one month and one year post-ICU discharge. Methods Data was prospectively collected on 309 patients over age 60 admitted to the Yale-New Haven Hospital Medical ICU between 2002 and 2004. Among survivors an assessment of ADL s and QOL was performed at one month and one-year post-ICU discharge. The SF-12 was scored using the version one norm based scoring with 1990 population norms. Multivariable regression was used to adjust the association between ADLs and QOL for important covariates. Results Our analysis of SF-12 data from 110 patients at one month post-ICU discharge showed that depression and ADL disability were associated with decreased QOL. Our model accounted for 17 of variability in SF12 physical scores PCS and 20 of variability in SF12 mental scores MCS . The mean PCS of 37 was significantly lower than the population mean whereas the mean MCS score of 51 was similar to the population mean. At one year mean PCS scores improved and ADL disability was no longer significantly associated with QOL. Mortality was 17 53 patients at ICU discharge 26 79 patients at hospital discharge 33 105 patients at one month post ICU admission and was 45 138 patients at one