tailieunhanh - báo cáo khoa học: " Two-stimuli manipulation of a biological motor"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Two-stimuli manipulation of a biological motor | Journal of Nanobiotechnology BioMed Central Short Communication Open Access Two-stimuli manipulation of a biological motor Zorica Ristic1 Marco Vitali2 5 Alessandro Duci3 Christian Goetze3 Klaus Kemnitz4 Werner Zuschratter2 Holger Lill1 and Dirk Bald 1 Address Department of Molecular Cell Biology VU University Amsterdam Amsterdam the Netherlands 2Leibniz-Institute for Neurobiology Magdeburg Germany 3arivis Multiple Imaging Tools Rostock Germany 4EuroPhoton Berlin Europhoton Berlin Germany and 5Technical University Berlin Germany Email Zorica Ristic - Marco Vitali - mvitali23@ Alessandro Duci - Christian Goetze - Klaus Kemnitz - klauskemnitz@ Werner Zuschratter - zuschratter@ Holger Lill - Dirk Bald - Corresponding author Published 15 May 2009 Received 17 February 2009 Journal of Nanobiotechnology 2009 7 3 doi l477-3l55-7-3 Accepted 15 May 2009 This article is available from http content 7 l 3 2009 Ristic et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract F1-ATPase is an enzyme acting as a rotary nano-motor. During catalysis subunits of this enzyme complex rotate relative to other parts of the enzyme. Here we demonstrate that the combination of two input stimuli causes stop of motor rotation. Application of either individual stimulus did not significantly influence motor motion. These findings may contribute to the development of logic gates using single biological motor molecules. Findings Biological nano-scale motors fulfil a broad range of tasks in living cells. Some motors like myosin kinesin and dynein move in .

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