tailieunhanh - báo cáo khoa học: "Quantum dot-induced cell death involves Fas upregulation and lipid peroxidation in human neuroblastoma cells"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Quantum dot-induced cell death involves Fas upregulation and lipid peroxidation in human neuroblastoma cells | Journal of Nanobiotechnology BioMed Central Research Open Access Quantum dot-induced cell death involves Fas upregulation and lipid peroxidation in human neuroblastoma cells Angela O Choi1 Sung Ju Cho1 2 Julie Desbarats3 Jasmina Lovric1 and Dusica Maysinger 1 Address Department of Pharmacology Therapeutics McGill University 3655 Promenade Sir William-Osler McIntyre Medical Sciences Building Montreal QC H3G 1Y6 Canada 2Faculty of Pharmacy and Department of Chemistry University of Montreal Pavillon J. A. Bombardier . 6128 Succursale Centre-Ville Montreal QC H3C 3J7 Canada and 3Department of Physiology McGill University Montreal QC H3G 1Y6 Canada Email Angela O Choi - Sung Ju Cho - Julie Desbarats - Jasmina Lovric - j_lovric@ Dusica Maysinger - Corresponding author Published 12 February 2007 Received 5 October 2006 . Accepted 12 February 2007 Journal of Nanobiotechnology 2007 5 1 doi l477-3l55-5-l This article is available from http content 5 l l 2007 Choi et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Neuroblastoma a frequently occurring solid tumour in children remains a therapeutic challenge as existing imaging tools are inadequate for proper and accurate diagnosis resulting in treatment failures. Nanoparticles have recently been introduced to the field of cancer research and promise remarkable improvements in diagnostics targeting and drug delivery. Among these nanoparticles quantum dots QDs are highly appealing due to their manipulatable surfaces yielding multifunctional QDs applicable in different biological models. The biocompatibility of these .