tailieunhanh - Health and Quality of Life Outcomes BioMed Central Research Open Access What is the relationship

Health and Quality of Life Outcomes BioMed Central Research Open Access What is the relationship between the minimally important difference and health state utility values? The case of the SF-6D Stephen J Walters* and John E Brazier Address: Sheffield Health Economics Group, School of Health and Related Research, University of Sheffield, Regent Court, 30 Regent Street, Sheffield, S1 4DA, UK Email: Stephen J Walters* - ; John E Brazier - * Corresponding author Published: 11 April 2003 Health and Quality of Life Outcomes 2003, 1:4 This article is available from: Received: 7 February 2003 Accepted: 11 April 2003 © 2003 Walters and Brazier; licensee BioMed Central Ltd | BioMed Central Health and Quality of Life Outcomes Research Open Access What is the relationship between the minimally important difference and health state utility values The case of the SF-6D Stephen J Walters and John E Brazier Address Sheffield Health Economics Group School of Health and Related Research University of Sheffield Regent Court 30 Regent Street Sheffield S1 4DA UK Email Stephen J Walters - John E Brazier - Corresponding author Published II April 2003 Received 7 February 2003 Accepted 1 1 April 2003 Health and Quality of Life Outcomes 2003 1 4 This article is available from http content 1 1 4 2003 Walters and Brazier licensee BioMed Central Ltd. This is an Open Access article verbatim copying and redistribution of this article are permitted in all media for any purpose provided this notice is preserved along with the article s original URL. Abstract Background The SF-6D is a new single summary preference-based measure of health derived from the SF-36. Empirical work is required to determine what is the smallest change in SF-6D scores that can be regarded as important and meaningful for health professionals patients and other stakeholders. Objectives To use anchor-based methods to determine the minimally important difference MID for the SF-6D for various datasets. Methods All responders to the original SF-36 questionnaire can be assigned an SF-6D score provided the 11 items used in the SF-6D have been completed. The SF-6D can be regarded as a continuous outcome scored on a to scale with indicating full health . Anchor-based methods examine the relationship between an health-related quality of life HRQoL measure and an independent measure or anchor to elucidate the meaning of a particular degree of change. One anchor-based approach uses an estimate of the MID the difference in the QoL scale corresponding to a self-reported small but important change on a global scale.

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