tailieunhanh - Health and Quality of Life Outcomes BioMed Central Research Open Access A new instrument for

Health and Quality of Life Outcomes BioMed Central Research Open Access A new instrument for measuring anticoagulation-related quality of life: development and preliminary validation Greg Samsa*1,3, David B Matchar2,4, Rowena J Dolor2,4, Ingela Wiklund5, Ewa Hedner5, Gail Wygant5, Ole Hauch5, Cheryl Beadle Marple5 and Roger Edwards6,7 Address: 1Department of Biometry and Bioinformatics, Duke University Medical Center, Wachovia Plaza, Suite 220, 2200 West Main Street, Durham NC 27705, USA, 2Department of Medicine, Duke University Medical Center, Durham NC, USA, 3Center for Clinical Health Policy Research, Duke University Medical Center, Durham NC, USA, 4Department of Veterans Affairs Medical Center, Durham NC, USA, 5AstraZeneca Pharmaceuticals, Stockholm, Sweden, 6Health Services. | BioMed Central Health and Quality of Life Outcomes Research Open Access A new instrument for measuring anticoagulation-related quality of life development and preliminary validation Greg Samsa 1 3 David B Matchar2 4 Rowena J Dolor2 4 Ingela Wiklund5 Ewa Hedner5 Gail Wygant5 Ole Hauch5 Cheryl Beadle Marple5 and Roger Edwards6 7 Address Department of Biometry and Bioinformatics Duke University Medical Center Wachovia Plaza Suite 220 2200 West Main Street Durham NC 27705 USA 2Department of Medicine Duke University Medical Center Durham NC USA 3Center for Clinical Health Policy Research Duke University Medical Center Durham NC USA 4Department of Veterans Affairs Medical Center Durham NC USA 5AstraZeneca Pharmaceuticals Stockholm Sweden 6Health Services Consulting Corporation Cambridge MA USA and 7TIAX Inc Cambridge MA USA Email Greg Samsa - samsa001@ David B Matchar- Rowena J Dolor- dolor001@ Ingela Wiklund - Ewa Hedner - Gail Wygant - Ole Hauch - Cheryl Beadle Marple - Roger Edwards - Corresponding author Published 06 May 2004 Received 15 March 2004 Accepted 06 May 2004 Health and Quality of Life Outcomes 2004 2 22 This article is available from http content 2 l 22 2004 Samsa et al licensee BioMed Central Ltd. This is an Open Access article verbatim copying and redistribution of this article are permitted in all media for any purpose provided this notice is preserved along with the article s original URL. Abstract Background Anticoagulation can reduce quality of life and different models of anticoagulation management might have different impacts on satisfaction with this component of medical care. Yet to our knowledge there are no scales measuring quality of life and satisfaction with anticoagulation that can be generalized across different models .