tailieunhanh - Báo cáo y học: " Collet-Sicard syndrome as an initial presentation of prostate cancer: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Collet-Sicard syndrome as an initial presentation of prostate cancer: a case report. | Villatoro et al. Journal of Medical Case Reports 2011 5 315 http content 5 1 315 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access Collet-Sicard syndrome as an initial presentation of prostate cancer a case report Rosa Villatoro 1 Carlos Romero2 and Antonio Rueda1 Abstract Background Collet-Sicard syndrome is caused by lesions at the base of the skull affecting the lower cranial nerves. It is associated with various etiologies of tumoral and other origin. Although this syndrome has been reported previously in the literature most cases are diagnosed as part of primary disease follow-up. This case is unusual because of the diagnosis of bone metastasis secondary to prostate cancer. Case presentation We present the case of a 70-year-old Caucasian man with a three-week history of headache and maxillary pain on the right side together with paresis of the low cranial nerves. This study was carried out with a computed tomography CT scan of the larynx and neck and MRI which revealed a bone lesion at the base of the skull affecting the right occipital condyle and part of the right side of the basilar bone. On the basis of differential diagnosis a fibrous dysplasia Paget s disease or metastasis was considered. Finally and after other studies were performed a diagnosis of bone metastasis secondary to prostate cancer was established. Conclusions We think that this case is curious because it involved an initial presentation of metastatic prostate cancer. It is important this should be considered in the differential diagnosis when a patient with unusual clinical findings is first seen in view of the fact that first-line hormonal treatment may control the disease for months or years. Background Collet-Sicard syndrome is caused by lesions at the base of the skull affecting the lower cranial nerves which produces dysphonia displacement of the palate and atony of the trapezius muscle and sternocleidomastoid as well as anesthesia of the larynx pharynx