tailieunhanh - Báo cáo y học: "Assessment of radiographic progression in the spines of patients with ankylosing spondylitis treated with adalimumab for up to 2 years"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Assessment of radiographic progression in the spines of patients with ankylosing spondylitis treated with adalimumab for up to 2 years. | Available online http content 11 4 R127 Research article Assessment of radiographic progression in the spines of patients with ankylosing spondylitis treated with adalimumab for up to 2 years Désirée van der Heijde1 David Salonen2 Barbara N Weissman3 Robert Landewe4 Walter P Maksymowych5 Hartmut Kupper6 Shaila Ballal7 Eric Gibson7 Robert Wong7 for the Canadian M03-606 study group and the ATLAS study group Department of Rheumatology C1 R Leiden University Medical Center PO Box 9600 2300 RC Leiden The Netherlands department of Medical Imaging University of Toronto 600 University Avenue Toronto ON M5G 1X5 Canada 3Brigham and Women s Hospital 75 Francis Street Boston MA 02115 USA department of Internal Medicine Rheumatology Maastricht University Medical Center PO Box 616 6200 MD Maastricht The Netherlands 5Medicine Rheumatic Disease Unit University of Alberta 562 Heritage Medical Research Building Edmonton AB T6G 2S2 Canada 6Abbott GmbH Co. KG Knollstrasse 50 Ludwigshafen 67061 Germany 7Formerly Abbott Laboratories 300 Interpace Parkway B Parsippany NJ 07054 USA Corresponding author Désirée van der Heijde Received 22 May 2009 Revisions requested 8 Jul 2009 Revisions received 7 Aug 2009 Accepted 24 Aug 2009 Published 24 Aug 2009 Arthritis Research Therapy 2009 11 R127 doi 86 ar2794 This article is online at http content 11 4 R127 2009 van der Heijde et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Ankylosing spondylitis AS is a chronic rheumatic disease associated with spinal inflammation that subsequently leads to progression of structural damage and loss of function. The fully human anti-tumor necrosis factor