tailieunhanh - Báo cáo y học: "Physical function, disease activity, and health-related quality-of-life outcomes after 3 years of adalimumab treatment in patients with ankylosing spondylitis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Physical function, disease activity, and health-related quality-of-life outcomes after 3 years of adalimumab treatment in patients with ankylosing spondylitis. | Available online http content 11 4 R124 Research article Physical function disease activity and health-related quality-of-life outcomes after 3 years of adalimumab treatment in patients with ankylosing spondylitis Désirée M van der Heijde1 Dennis A Revicki2 Katherine L Gooch3 Robert L Wong4 Hartmut Kupper5 Neesha Harnam2 Chris Thompson2 Joachim Sieper6 for the ATLAS Study Group Department of Rheumatology Leiden University Medical Center Leiden PO Box 9600 2300 RC Leiden The Netherlands 2Center for Health Outcomes Research United BioSource Corporation 7101 Wisconsin Avenue Suite 600 Bethesda Maryland 20814 USA 3Global Health Economics and Outcomes Research Abbott Laboratories 1 00 Abbott Park Road Abbott Park Illinois 60064 USA 4Formerly Abbott Immunology Abbott Laboratories 300 Interpace Parkway Parsippany New Jersey 07054 USA 5Abbott GmbH Co. KG Knollstrasse 50 Ludwigshafen 67061 Germany 6Medical Department I Rheumatology Charité Campus Benjamin Franklin and German Rheumatism Research Center Hindenburgdamm 30 Berlin 12200 Germany Corresponding author Désirée M van der Heijde Received 14 Apr 2009 Revisions requested 5 Jun 2009 Revisions received 16 Jul 2009 Accepted 1 7 Aug 2009 Published 1 7 Aug 2009 Arthritis Research Therapy 2009 11 R124 doi 86 ar2790 This article is online at http content 11 4 R124 2009 van der Heijde et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction We evaluated the three-year impact of adalimumab on patient-reported physical function and health-related quality-of-life HRQOL outcomes in patients with active ankylosing spondylitis AS . Methods The Adalimumab Trial Evaluating Long-Term .