tailieunhanh - Báo cáo y học: "Measuring metacarpal cortical bone by digital x-ray radiogrammetry: a step forward"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Measuring metacarpal cortical bone by digital x-ray radiogrammetry: a step forward? | Available online http content 11 5 127 Editorial Measuring metacarpal cortical bone by digital x-ray radiogrammetry a step forward Piet P Geusens1 2 and Willem F Lems3 1 Department of Internal Medicine Subdivision of Rheumatology Maastricht University Medical Centre P. Debyelaan 25 Postbus 5800 6202 AZ Maastricht The Netherlands 2Biomedical Research Institute Hasselt University Agoralaan gebouw D B-3590 Diepenbeek Belgium 3Department of Rheumatology Vrije Universiteit Medical Centre 3A64 Postbus 7057 1007 MB Amsterdam The Netherlands Corresponding author Piet P Geusens Published 1 October 2009 Arthritis Research Therapy 2009 11 127 doi ar2788 This article is online at http content 11 5 127 2009 BioMed Central Ltd See related research by Boyesen et al. http content 11 4 R103 Abstract Changes in metacarpal cortical bone mineral density BMD using digital x-ray radiogrammetry were studied in patients with early rheumatoid arthritis. After 1 2 and 5 years large BMD losses were found and respectively. Elevated erythrocyte sedimentation rate and anti-cyclic citrullinated peptide levels were independent predictors of bone loss indicating that the largest amount of bone loss was found in patients with severe inflammation and high production of auto-antibodies who are known to be at the highest risk of developing radiological bone damage. Studies are needed about the spatial and time relationship between erosions and juxta-articular and metacarpal bone loss. The elegant study by Boyesen and colleagues 1 in the previous issue of Arthritis Research Therapy in which they observed the changes in hand bone mineral density BMD using digital x-ray radiogrammetry DXR in 163 patients with early rheumatoid arthritis RA is most welcome. DXR measures the cortical thickness width and porosity of the central parts of metacarpals 2 to 4. After 1 2 and 5 years of observation .