tailieunhanh - báo cáo khoa học: "Transient psychosis due to painless thyroiditis in a patient with anxiety disorder: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:Transient psychosis due to painless thyroiditis in a patient with anxiety disorder: a case report | Kobayashi et al. Journal of Medical Case Reports 2011 5 534 http content 5 1 534 WV journalof medical l rCASE REPORTS CASE REPORT Open Access Transient psychosis due to painless thyroiditis in a patient with anxiety disorder a case report Nobuyuki Kobayashi1 Junichi Tajiri2 and Masahiro Takano3 Abstract Introduction There are few reports on thyrotoxic psychosis caused by diseases other than Graves disease or toxic nodular goiter. Case presentation A 64-year-old Japanese woman was treated for anxiety disorder in our clinic for 10 years. She had five episodes of transient psychosis during the first five years. When she developed psychosis without neck pain 10 years after her first visit a laboratory reexamination revealed that she had subclinical hyperthyroidism and tested positive for antithyroid autoantibodies negative for thyroid stimulating hormone receptor antibody and had decreased radioactive iodine uptake. She was diagnosed as having painless thyroiditis. The hyperthyroidism disappeared within a month and the psychosis lasted for three months. Conclusion To the best of our knowledge this is the first report of psychosis due to painless thyroiditis-induced hyperthyroidism. Physical symptoms of painless thyroiditis are often so mild that careful differential diagnosis is necessary in the cases of transient psychosis. Introduction Hyperthyroid patients frequently develop mental symptoms 1 2 such as anxiety irritability unstable mood fatigue and insomnia. However psychosis is a rare complication 3 4 . Many cases of psychosis that were induced by thyrotoxicosis or thyrotoxic psychosis were caused by Graves disease or a toxic nodular goiter. Although destructive thyroiditis is the next most common cause of hyperthyroidism only one case each of postpartum thyroiditis 5 and subacute thyroiditis 6 have been reported to induce psychosis. We report on a patient with anxiety disorder who experienced transient psychosis due to the development .