tailieunhanh - báo cáo khoa học: "Persisting right-sided chylothorax in a patient with chronic lymphocytic leukemia: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Persisting right-sided chylothorax in a patient with chronic lymphocytic leukemia: a case report | PR JOURNALOF MEDICAL Ur CASE reports Persisting right-sided chylothorax in a patient with chronic lymphocytic leukemia a case report Scholz et al. 2 BioMed Central Scholz et al. Journal of Medical Case Reports 2011 5 492 http content 5 1 492 3 October 2011 Scholz et al. Journal of Medical Case Reports 2011 5 492 http content 5 1 492 JOURNALOF medical Ur Case REPORTS CASE REPORT Open Access Persisting right-sided chylothorax in a patient with chronic lymphocytic leukemia a case report ml I . 1 . M-zd A c r f I 71 I_I ms. u- I s Cl r I 12 c I c o rm mi I3 A ml rr 4 ỉ ms ml rm-i r h l-sml r msr-r ms1 -I m ml uoaenara A Scholz roria Sirbu Sabine Semrau Katharina Anders Andreas Mackensen ana Bernd M Spriewald1 Abstract Introduction Chylothorax caused by chronic lymphocytic leukemia is very rare and the best therapeutic approach especially the role of modern immunochemotherapy is not yet defined. Case presentation We present the case of a 65-year-old male Caucasian patient with right-sided chylothorax caused by a concomitantly diagnosed chronic lymphocytic leukemia. As first-line treatment four cycles of an immunochemotherapy consisting of fludarabine cyclophosphamide and rituximab were administered. In addition our patient received total parenteral nutrition for the first two weeks of treatment. Despite the very good clinical response of the lymphoma to treatment the chylothorax persisted and percutaneous radiotherapy of the thoracic duct was applied. rowever eight weeks after the radiotherapy the chylothorax still persisted and our patient agreed to a surgical intervention. A ligation of the thoracic duct via a muscle sparing thoracotomy was performed resulting in a complete cessation of the pleural effusion. Apart from the first two weeks our patient was treated on an out-patient basis for nearly six months. Conclusion In this case of chylothorax caused by chronic lymphocytic leukemia immunochemotherapy in .