tailieunhanh - Báo cáo y học: "How much sleep apnea is too much? Authors’ response"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài:How much sleep apnea is too much? Authors’ response. | Available online http content 11 4 410 Letter How much sleep apnea is too much Authors response David M Rapoport1 Fumiharu Togo2 and Benjamin H Natelson3 1 Department of Medicine Division of Pulmonary and Critical Care Medicine NYU School of Medicine New York NY 10016 USA 2Department of Work Stress Control Japan National Institute of Occupational Safety and Health Kawasaki 214-8585 Japan 3Pain and Fatigue Study Center Department of Pain Medicine and Palliative Care Beth Israel Medical Center New York NY 10003 USA Corresponding author Benjamin H. Natelson bnatelson@ Published 15 July 2009 Arthritis Research Therapy 2009 11 410 doi ar2691 This article is online at http content 11 4 410 2009 BioMed Central Ltd See related research by Togo et al. http content 10 3 R56 and related letter by Martinez et al. http content 11 4 410 Our study 1 had two main purposes first to examine the occurrence of sleep-disordered breathing SDB in patients with chronic fatigue syndrome CFS and then to exclude patients with this confound in order to evaluate the structure of sleep in a group of patients with pure CFS to look for relations with the symptoms of fatigue and sleepiness. In order to do this we had to define an upper limit for the occurrence of respiratory events that might explain the daytime symptoms. Martinez and Cassol are correct that the currently accepted cutpoint for abnormality proposed by the American Academy of Sleep Medicine AASM and Centers for Medicare Medicaid Services CMS in the US is an apnea-hypopnea index AHI 5 per hour but less than 15 per hour - but only if symptoms such as EDS are present. However the AHI is an insensitive measure of the severity of mild respiratory events such as respiratory event-related arousals RERAs as it requires either a 3 or 4 desaturation for the definition of hypopnea and this is frequently not present in respiratory

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