tailieunhanh - Báo cáo y học: "Peripheral arterial disease in polymyalgia rheumatica"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài:Peripheral arterial disease in polymyalgia rheumatica. | Available online http content 11 3 111 Editorial Peripheral arterial disease in polymyalgia rheumatica Frances A Borg and Bhaskar Dasgupta Department of Rheumatology Southend University Hospital Prittlewell Chase Westcliffe-on-Sea Essex SS0 0RY UK Corresponding author Bhaskar Dasgupta Published 20 May 2009 Arthritis Research Therapy 2009 11 111 doi ar2685 This article is online at http content 11 3 111 2009 BioMed Central Ltd See related research article by Warrington et al. http content 11 2 R50 Abstract Patients with polymyalgia rheumatica have been shown to have an increased risk of peripheral arterial disease on longitudinal followup. Possible explanations for this include premature atherosclerosis related to chronic inflammation as with other inflammatory rheuma-tological conditions. Alternatively polymyalgia rheumatica can be associated with vasculitis even in the absence of clinical giant cell arteritis and peripheral vascular disease may represent subclinical vasculitis. Further work is required to elucidate the reasons for this increased risk. Currently it would remain reasonable to aggressively control modifiable atherosclerotic risk factors. Introduction Warrington and colleagues report an increased risk of peripheral arterial disease PAD in patients with polymyalgia rheumatica PMR compared with matched controls 1 . They found that 38 out of 353 PMR patients developed PAD versus 28 out of 705 control subjects over a median followup of 11 years hazard ratio adjusted for conventional cardiovascular risk factors 95 confidence interval to . The same centre previously reported an increased likelihood of coronary and cerebrovascular disease in PMR 2 . The authors speculate that possible explanations for this are premature atherosclerosis related to inflammation or the presence of subclinical vasculitis. Premature atherosclerosis and .

TÀI LIỆU LIÊN QUAN
TỪ KHÓA LIÊN QUAN
crossorigin="anonymous">
Đã phát hiện trình chặn quảng cáo AdBlock
Trang web này phụ thuộc vào doanh thu từ số lần hiển thị quảng cáo để tồn tại. Vui lòng tắt trình chặn quảng cáo của bạn hoặc tạm dừng tính năng chặn quảng cáo cho trang web này.