tailieunhanh - Báo cáo y học: "Increased levels of circulating microparticles in primary Sjögren's syndrome, systemic lupus erythematosus and rheumatoid arthritis and relation with disease activity"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Increased levels of circulating microparticles in primary Sjögren's syndrome, systemic lupus erythematosus and rheumatoid arthritis and relation with disease activity. | Available online http content 11 5 R156 Research article Increased levels of circulating microparticles in primary Sjogren s syndrome systemic lupus erythematosus and rheumatoid arthritis and relation with disease activity Jeremie Sellam1 Valérie Proulle2 Astrid Jungel3 Marc Ittah1 Corinne Miceli Richard1 Jacques-Eric Gottenberg1 Florence Toti4 Joelle Benessiano5 Steffen Gay3 Jean-Marie Freyssinet4 and Xavier Mariette1 Open Access 1Rhumatologie Hôpital Bicêtre Assistance Publique-Hôpitaux de Paris AP-HP INSERM U802 Université Paris-Sud 11 78 rue du General Leclerc 94270 Le Kremlin Bicêtre France 2Hématologie Hôpital Bicêtre APHP INSERM U770 Université Paris-Sud 11 78 rue du General Leclerc 94270 Le Kremlin Bicêtre France 3Center of Experimental Rheumatology University Hospital Zurich Gloriastrasse 25 CH 8091 Zurich Switzerland 4INSERM Unite 770 et Universite de Strasbourg 78 rue du General Leclerc 94270 Le Kremlin Bicêtre France 5Centre de Ressources biologiques - Centre d Investigation clinique Hôpital Bichat AP-HP 46 rue Henri-Huchard 7501 8 Paris France Corresponding author Xavier Mariette Received 6 Aug 2009 Revisions requested 27 Aug 2009 Revisions received 22 Sep 2009 Accepted 15 Oct 2009 Published 15 Oct 2009 Arthritis Research Therapy 2009 11 R156 doi 86 ar2833 This article is online at http content 11 5 R156 2009 Sellam et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Cell stimulation leads to the shedding of phosphatidylserine PS -rich microparticles MPs . Because autoimmune diseases AIDs are characterized by cell activation we investigated level of circulating MPs as a possible biomarker in primary Sjogren