tailieunhanh - báo cáo khoa học: "Uneventful octreotide LAR therapy throughout three pregnancies, with favorable delivery and anthropometric measures for each newborn: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Uneventful octreotide LAR therapy throughout three pregnancies, with favorable delivery and anthropometric measures for each newborn: a case report | Naccache et al. Journal of Medical Case Reports 2011 5 386 http content 5 1 386 JOURNALOF medical case reports CASE REPORT Open Access Uneventful octreotide LAR therapy throughout three pregnancies with favorable delivery and anthropometric measures for each newborn a case report 1 A 7 1 l l - 1 1 2 3 Deeb Daoud Naccache Adnan Zaina Zila Shen-Or Michal Armoni George Kontogeorgos and Ali Yahia Abstract Introduction The safety of octreotide use in its short-acting preparation in pregnancy is still unclear. This report provides the first documentation of uneventful octreotide LAR use during three pregnancies in a woman with bronchial carcinoid-associated adrenocorticotropic hormone-dependent Cushing s syndrome. Case presentation A 25-year-old Arabic woman presented to our emergency department with rapid onset of headache flaring acne and hirsutism facial puffiness weight gain and paroxysmal myopathy and paranoiac thoughts of rape and sexual intimidation. After undergoing surgical removal of a mass by left lower lung lobectomy her residual lung disease medical therapy failed. Chronic octreotide LAR injections were initiated as indicated by a positive octreoscan. Follow-up revealed a long-lasting positive response to octreotide. Avidity of octreotide to somatostatin receptor sub-type 2 was later confirmed by a positive somatostatin receptor sub-type 2 in the resected tumor specimen. Against our instructions the patient had three spontaneous pregnancies leading to delivery of three full-term healthy children while her octreotide LAR therapy continued. Conclusion This case adds more data supporting the potential for the safe use of octreotide and the feasibility of octreotide LAR use during pregnancy making compliance with the patient s preference not to withdraw octreotide therapy as soon as her pregnancy is confirmed a thoughtful option. Introduction The safety of octreotide use during pregnancy does not lend itself to conducting a controlled

TÀI LIỆU LIÊN QUAN
crossorigin="anonymous">
Đã phát hiện trình chặn quảng cáo AdBlock
Trang web này phụ thuộc vào doanh thu từ số lần hiển thị quảng cáo để tồn tại. Vui lòng tắt trình chặn quảng cáo của bạn hoặc tạm dừng tính năng chặn quảng cáo cho trang web này.