tailieunhanh - báo cáo khoa học: "Takayasu’s arteritis presenting with temporary loss of vision in a 23-year-old woman with beta thalassemia trait: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Takayasu’s arteritis presenting with temporary loss of vision in a 23-year-old woman with beta thalassemia trait: a case report | Ishaq and Shabbir Journal of Medical Case Reports 2011 5 466 http content 5 1 466 JOURNALOF medical Ur Case REPORTS CASE REPORT Open Access Takayasu s arteritis presenting with temporary loss of vision in a 23-year-old woman with beta thalassemia trait a case report Mohammad G Ishaq and Fahad A Shabbir Abstract Introduction The simultaneous presence of Takayasu s arteritis and beta thalassemia trait is a rare combination. To the best of our knowledge this is the first case report on Takayasu s arteritis and beta thalassemia presenting together. Case presentation This is a case report of a 23-year-old Asian woman of Pakistani descent who presented with a headache blurred vision and dizziness. Conclusion The correct diagnosis of our patient was based on clinical suspicion appropriate imaging studies and deliberation of the differential diagnosis. The management of our patient depended on the correct diagnosis of both the diseases. Introduction Takayasu s arteritis TA is an autoimmune chronic progressive large-vessel vasculitis that usually affects young adults especially women. The disease can affect all races and ethnic groups. The diffuse nature of this vasculitis can involve multiple organ systems to varying degrees and can present with a wide range of symptoms 1 with an incidence of one to two cases per million people per year 2 . Beta thalassemia trait is an autosomal recessive disorder characterized by a point mutation on the beta-globin chain gene on chromosome 11 resulting in the defective synthesis of the beta-globin chain of hemoglobin 3 . To the best of our knowledge the incidence of TA with beta thalassemia trait has not previously been reported in the literature. Case Presentation A 23-year-old Asian woman of P akistani descent presented with blackouts blurring of vision and headache for more than two months duration. The headaches started in the frontal region then radiated to the whole head were moderate in intensity and .