tailieunhanh - Báo cáo y học: "Biochemical markers of bone turnover and their association with bone marrow lesions"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Biochemical markers of bone turnover and their association with bone marrow lesions. | Available online http content 10 4 R102 Research article Biochemical markers of bone turnover and their association with bone marrow lesions David J Hunter1 2 Michael LaValley1 Jiang Li1 Doug C Bauer3 Michael Nevitt3 Jeroen DeGroot4 Robin Poole5 David Eyre6 Ali Guermazi1 Daniel Gale7 Saara Totterman7 and David T Felson1 Department of Epidemiology and Biostatistics Boston University School of Medicine Albany Street Boston Massachusetts 02118 USA 2New England Baptist Hospital Parker Hill Avenue Boston Massachusetts 02120 USA 3University of California at San Francisco Berry Street San Francisco California 94107 USA 4TNO Quality of Life Business Unit Biomedical Research Zernikedreef 9 2333 CK Leiden The Netherlands 5Joint Diseases Laboratory McGill University Cedar Avenue Quebec H3G 1A6 Canada 6Department of Orthopaedics and Sports Medicine University of Washington NE Pacific Street Seattle Washington 98195 USA 7Virtualscopics Linden Oaks Rochester New York 14625 USA Corresponding author David J Hunter djhunter@ Received 11 Jan 2008 Revisions requested 20 Mar 2008 Revisions received 15 Aug 2008 Accepted 29 Aug 2008 Published 29 Aug 2008 Arthritis Research Therapy 2008 10 R102 doi ar2494 This article is online at http content 10 4 R102 2008 Hunter et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Our objective was to determine whether markers of bone resorption and formation could serve as markers for the presence of bone marrow lesions BMLs . Methods We conducted an analysis of data from the Boston Osteoarthritis of the Knee Study BOKS . Knee magnetic resonance images were scored for BMLs using a semiquantitative grading scheme. .