tailieunhanh - Báo cáo y học: "Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases. | Available online http content 11 3 229 Review Epidemiological studies in incidence prevalence mortality and comorbidity of the rheumatic diseases Sherine E Gabriel1 and Kaleb Michaud2 3 1 Department of Health Sciences Research Mayo Foundation First St. SW Rochester MN 55905 USA 2Nebraska Arthritis Outcomes Research Center University of Nebraska Medical Center Omaha NE 68198 USA 3National Data Bank for Rheumatic Diseases N Emporia Wichita KS 67214 USA Corresponding author Sherine E Gabriel Published 19 May 2009 This article is online at http content 11 3 229 2009 BioMed Central Ltd Arthritis Research Therapy 2009 11 229 doi ar2669 Abstract Epidemiology is the study of the distribution and determinants of disease in human populations. Over the past decade there has been considerable progress in our understanding of the fundamental descriptive epidemiology levels of disease frequency incidence and prevalence comorbidity mortality trends over time geographic distributions and clinical characteristics of the rheumatic diseases. This progress is reviewed for the following major rheumatic diseases rheumatoid arthritis RA juvenile rheumatoid arthritis psoriatic arthritis osteoarthritis systemic lupus erythematosus giant cell arteritis polymyalgia rheumatica gout Sjogren s syndrome and ankylosing spondylitis. These findings demonstrate the dynamic nature of the incidence and prevalence of these conditions - a reflection of the impact of genetic and environmental factors. The past decade has also brought new insights regarding the comorbidity associated with rheumatic diseases. Strong evidence now shows that persons with RA are at a high risk for developing several comorbid disorders that these conditions may have atypical features and thus may be difficult to diagnose and that persons with RA experience poorer outcomes after comorbidity compared with the general population. Taken together these .

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