tailieunhanh - báo cáo khoa học: "Complications of Evans' syndrome in an infant with hereditary spherocytosis: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:Complications of Evans' syndrome in an infant with hereditary spherocytosis: a case report | Journal of Hematology Oncology BioMed Central Open Access Complications of Evans syndrome in an infant with hereditary spherocytosis a case report Hideki Yoshida 1 Hiroyuki Ishida1 Takao Yoshihara1 Takashi Oyamada2 Masataka Kuwana3 Toshihiko Imamura4 and Akira Morimoto4 Address Department of Pediatrics Matsushita Memorial Hospital Moriguchi Japan 2Department of Forensic Medicine Jichi medical University Tochigi Japan 3Division of Rheumatology Department of Internal Medicine Keio University Tokyo Japan and 4Department of Pediatrics Kyoto Prefectural University of Medicine Kyoto Japan Email Hideki Yoshida - hide0519@ Hiroyuki Ishida- Takao Yoshihara - Takashi Oyamada - kmskt@ Masataka Kuwana - kuwanam@ Toshihiko Imamura - timamura@ Akira Morimoto - akira@ Corresponding author Published 10 September 2009 Received 2 April 2009 Journal of Hematology Oncology 2009 2 40 doi 1756-8722-2-40 Accepted 10 September 2009 This article is available from http content 2 1 40 2009 Yoshida et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Hereditary spherocytosis HS is a genetic disorder of the red blood cell membrane clinically characterized by anemia jaundice and splenomegaly. Evans syndrome is a clinical syndrome characterized by autoimmune hemolytic anemia AIHA accompanied by immune thrombocytopenic purpura ITP . It results from a malfunction of the immune system that produces multiple autoantibodies targeting at least red blood cells and platelets. HS and Evans syndrome have different mechanisms of pathophysiology one another. We reported the quite rare case of