tailieunhanh - báo cáo khoa học: "Aggressive juvenile fibromatosis of the paranasal sinuses: case report and brief review"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:Aggressive juvenile fibromatosis of the paranasal sinuses: case report and brief review | BioMed Central Journal of Hematology Oncology Open Access Case report Aggressive juvenile fibromatosis of the paranasal sinuses case report and brief review Shaheen E Lakhan 1 Robert M Eager2 and Lindsey Harle2 Address Executive Director Global Neuroscience Initiative Foundation Los Angeles CA USA and 2Research Consultant Department of Biomedical Sciences Global Neuroscience Initiative Foundation Los Angeles CA USA Email Shaheen E Lakhan - slakhan@ Robert M Eager - rmeager@ Lindsey Harle - lharle@ Corresponding author Published 28 May 2008 Received 23 April 2008 Journal of Hematology Oncology 2008 1 3 doi 1756-8722-1 -3 Accepted 28 May 2008 This article is available from http content 1 1 3 2008 Lakhan et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Desmoid fibromatoses are benign slow growing fibroblastic neoplasms arising from musculoaponeurotic stromal elements. Desmoids are characterized by local invasion with a high rate of local recurrence and a tendency to destroy adjacent structures and organs. Desmoid fibromatoses are rare in children and though they may occur in the head and neck region are extremely rare in the paranasal sinuses. Here we report a case of extraabdominal desmoid fibromatosis in a seven-year-old boy involving the sphenoid sinus one of only six published reports of desmoid fibromatosis of the paranasal sinuses. The expansile soft tissue mass eroded the walls of the sphenoid sinus as well as the posterior ethmoid air cells extending cephalad through the base of the skull. We discuss the clinicopathologic features of this lesion including structural and ultrastructural characteristics and we review the literature regarding treatment and .