tailieunhanh - báo cáo khoa học: "Treatment of malignant tumors of the skull base with multi-session radiosurgery"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:Treatment of malignant tumors of the skull base with multi-session radiosurgery | Journal of Hematology Oncology BioMed Central Research Treatment of malignant tumors of the skull base with multi-session radiosurgery Nicholas D Coppa1 Daniel MS Raper4 Ying Zhang3 Brian T Collins2 K William Harter2 Gregory J Gagnon2 Sean P Collins2 and Walter C Jean 1 2 Open Access Address Department of Neurosurgery Georgetown University Hospital Washington DC USA 2Department of Radiation Oncology Georgetown University Hospital Washington DC USA 3Biostatistics Unit Lombardi Comprehensive Cancer Center Georgetown University Medical Center Washington DC USA and 4Faculty of Medicine University of Sydney Sydney Australia Email Nicholas D Coppa - ndcoppa@ Daniel MS Raper - drap7157@ Ying Zhang - yz9@ Brian T Collins - collinsb@ K William Harter-harterk@ Gregory J Gagnon - gagnong@ Sean P Collins - mbppkia@ Walter C Jean - WCJ4@ Corresponding author Published 2 April 2009 Received 18 January 2009 Journal of Hematology Oncology 2009 2 16 doi 1756-8722-2-16 Accepted 2 April 2009 This article is available from http content 2 1 16 2009 Coppa et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Objective Malignant tumors that involve the skull base pose significant challenges to the clinician because of the proximity of critical neurovascular structures and limited effectiveness of surgical resection without major morbidity. The purpose of this study was to evaluate the efficacy and safety of multi-session radiosurgery in patients with malignancies of the skull base. Methods Clinical and radiographic data for 37 patients treated with image-guided multi-session .