tailieunhanh - Báo cáo y học: "Acral lentiginous melanoma of the foot and ankle: A case series and review of the literature"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Acral lentiginous melanoma of the foot and ankle: A case series and review of the literature. | Journal of Foot and Ankle Research BioMed Central Research Acral lentiginous melanoma of the foot and ankle A case series and review of the literature Ivan R Bristow 1 and Katharine Acland2 Open Access Address 1School of Health Sciences University of Southampton UK and 2St Johns Institute of Dermatology St Thomas Hospital London UK Email Ivan R Bristow - ib@ Katharine Acland - ib@ Corresponding author Published 15 September 2008 Received 13 May 2008 . . . Accepted 15 September 2008 Journal of Foot and Ankle Research 2008 1 11 doi l757-ll46-l-ll This article is available from http content l l ll 2008 Bristow and Acland licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Acral lentiginous melanoma ALM is an uncommon cutaneous malignant tumour which may arise on the foot. Its relative rarity atypical appearance and late presentation frequently serve as poor prognostic indicators. Methods At a tertiary skin tumour centre a retrospective review was undertaken of all patients diagnosed with the tumour at the level of ankle or below. Results Over a six year period 27 cases 20 female 7 male were identified with positive histology confirming the disease. The age ranged from 35-96 years of age mean years . The majority of the cohort were white 59 with plantar lesions 62 . 33 of patients were initially were diagnosed incorrectly. The average time taken from the point of recognition by the patient to the lesion being correctly diagnosed was around months. Conclusion Earlier diagnosis of ALM requires education at both a patient and practitioner level. Background Melanoma is a malignant tumour arising from melanocytes. The number of cases of the disease .