tailieunhanh - Báo cáo y học: "Frequency of intravascular large B-cell lymphoma in Japan: Study of the Osaka Lymphoma Study Group"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Frequency of intravascular large B-cell lymphoma in Japan: Study of the Osaka Lymphoma Study Group. | Chihara et al. Journal of Hematology Oncology 2011 4 14 http content 4 1 14 JOURNAL OF HEMATOLOGY ONCOLOGY LETTER TO THE EDITOR Open Access Frequency of intravascular large B-cell lymphoma in Japan Study of the Osaka Lymphoma Study Group 11 111 2 3 Takeshi Chihara Naoki Wada Junichiro Ikeda Shigeki Fujita Yumiko Hori Hiroyasu Ogawa Haruo Sugiyama s4 5 li z 6 7 1 1 Shosaku Nomura Itaru Matsumura Masayuki Hino Yuzuru Kanakura Eiichi Morii and Katsuyuki Aozasa Dear Editor Intravascular large B-cell lymphoma B-IVL is listed as a distinct disease entity in the World Health Organi-zation WHO classification for lymphoid neoplasms 1 . The disease is rare and information for its exact frequency among non-Hodgkin lymphoma NHL has been extremely limited. There have been several reports mainly from Asian countries describing the different disease frequencies 2-4 . In addition population of the cases was variously described among these reports. Therefore it is difficult to know the geographical difference in disease frequency which might be helpful for understanding pathogenesis of disease. From November 1999 to December 2010 a total of 5 085 cases were registered with the Osaka Lymphoma Study Group OLSG which was established in 1999 and more than 60 institutes in Osaka area Japan participate to it. All of the hematoxylin and eosin-and immunoperoxidase-stained sections were reviewed by one of the authors KA . A diagnosis of malignant lymphoma was confirmed in 4 066 cases . Of these 4 066 cases 3 726 were NHL and 340 Hodgkin lymphoma. Number of cases with DLBCL and B-IVL was 1 815 of all ML of NHL and 9 of all ML of NHL respectively. Histologic criteria for the diagnosis of B-IVL is selective growth of B-lymphoid cells usually with large size within lumina of small or intermediated vessels. 9 cases of B-IVL in OLSG were summarized in Table 1. The median age of the B-IVL patients 67 years old at biopsy for diagnosis in the .